Therapies with hyaluronic acid for lips and wrinkles

Before injecting hyaluronic acid in lips, or cheekbones, or in the nasogenian folds, it would be useful to know a few details about it, exploring the myths surrounding it. Thus, it is said that the hyaluronic acid is “something unnatural”. False.

Hyaluronic acid is a substance naturally present in the human body and in the skin (derma) in particular. Hyaluronic acid used in the injectable therapies is of non-animal origin, being obtained by a complex synthesis process. 

It is microbiologically pure and is packed in syringes or in sterile vials. It has the consistency of a gel and it can be crosslinked or noncrosslinked, with or without anesthesia (lidocaine).

How long is the hyaluronic acid holding after being injected?

The viscoelastic gels of crosslinked hyaluronic acid are created for correcting the nasogenien folds, the fine lines, the facial line or the partial or full lip augmentation. 

The effects are immediate and hold for 6 to 18-24 months depending on the factors such as: skin type, wrinkles visibility, injection area, injection quantity etc.

What can be corrected by using hyaluronic acid?

The facial volumetry with the rejuvenation of the facial oval is an important concern at this moment. When aging all the structures starting with the tegument and ending with the bone structure of the face suffer changes, descending to the lower region and creating the reversed triangle (with the lower base), resulting in the „dropped” look of the face. 

By using the crosslinked and/or non crosslinked hyaluronic acid we can contribute to the remaking of the facial look in areas such as cheekbones, zigomatic lower area, mandibular area, menton.

dermatoestetica terapii acid hialuronic - skinmed

Is injecting of hyaluronic acid painful?

It is a minimally invasive procedure, almost painless and is carried out after the topic application of anesthetics. 

The effect is immediately visible, without prior precautions and durable in time between 6-12 months and two years. 

There are rarely described any local reactions, where the injection has been taken, such as: erythema/redness, contusions or bruises, pain or slight pruritus, that go away within 24 hours and 8 days (in average 72 hours). 

 There can occur indurations, granuloma or nodules that last between 15 days and 3 months. 

Cases of reversible coloration of the injecting area are extremely rare and very rare a necrosis can occur in cases of intravascular shot.

It is an extremely valuable procedure, well known today, still scientifically expending, with molecules updating, the results being shortly after visible and showing no unpleasant injection-associated incidents.


Dermal fillers are substances used in facial aesthetic treatments that are injected into the skin. There are substances specifically designed to reduce wrinkles, to shape or to create volume. They are based on hyaluronic acid, a naturally occurring substance in the skin, whose production decreases with aging.

Hyaluronic acid is a natural molecule found in almost all living organisms. It has the ability to attract and bind water, having a role in lubricating and absorbing mechanical shock in joints; it also has an important role in nutrient transport and in maintaining optimal hydration in the skin.

By increasing the concentration of hyaluronic acid in the skin, the fillers have the property of revitalizing, restoring the volume of the skin, alleviating fine lines and wrinkles. The fillers are injectable in the form of gel, hyaluronic acid of non-animal origin. The hyaluronic acid  has a very close structure to that normally found in the body, with a long-lasting effect without being permanent.

Dermal injections with fillers are an easy way to reduce wrinkles, improve skin texture for a younger look. The results are seen after a single treatment session and are maintained for a period of 6 to 18 months. The injecting fillers give a natural look that does not affect the expressiveness of the face.

At Skinmed Clinic we use top quality hyaluronic acid with numerous back safety studies that guarantee its safety and efficacy. As closely related molecules as the structure of hyaluronic acid present naturally in tissues, the risk of allergic reactions is minimized.

Fillers can be used to soften and fill fine lines and wrinkles, to create a fuller look for the lips, for contouring the face and restoring the volume.

  • Nasolabial folds
  • Marionette lines
  • Wrinkles between eyebrows (glabella)
  • Lips (volume and contour)
  • Cheeks bones


During the initial medical exam, the dermatologist will discuss with you about your expectations from this treatment, recommending the treatment best suited to you, depending on the particularities of each patient.

During the procedure

The filler will be injected into the skin using a fine needle. The treatment generally lasts between 15 and 30 minutes, depending on the area treated and the amount of hyaluronic acid injected. The hyaluronic acid thus injected replenishes the volume, fills the lines and wrinkles, outlines the treated area, preserving the facial expressions unaltered.


Dermal fillers are biodegradable substances, which means they will normally disappear from the tissues. To ensure that the results are maintained, a second treatment session is recommended 6-12 months after the initial session. Moreover, the dermatologist will establish a schedule for a check up shortly after the procedure.

Immediately after treatment, local reactions such as redness, pruritus, small bruising, and minor pain in the area may occur. These are usually mild to moderate and disappear shortly after injection.


One of the advantages of dermal fillers is the maintaining of  the results over a long period of time; however, they are not permanent. Usually, a new treatment session is recommended at 8-12 months, depending on the particularities of each patient (age, lifestyle, type of skin, etc.).

Most people can benefit from this treatment to:

  • Reduce lines and wrinkles
  • Create lighter, fuller lips
  • Shape and redo the volume of face structures (cheekbones, chins)
  • Improve the texture and appearance of the skin (face, neck, neck or hands)

Fillers are not used in areas where there are active skin infections, inflammation or other skin conditions.

Not recommended for pregnant or breastfeeding women, people with autoimmune disorders or immunosuppressive therapy, or those predisposed to infection.

Generally, treatment with pain killers is not necessary. The procedure is performed after an anesthetic cream has been applied in advance to significantly reduce the discomfort. In the case of the lip, a sensitive area, fillers that use lidocaine, an anesthetic substance, are used to make the treatment as comfortable as possible.

Annually, more than 2 million procedures are performed worldwide involving injection of fillers. Allergic reactions are extremely rare. Immediately after injection, redness, swelling, pain, pruritus, bruising may occur, and may be mild to moderate, and disappear within a few days until one week after the procedure. After the augmentation of the lips, edema may develop, which begins to decrease in intensity after the first 2 days.

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